Cargando…

Docking Studies and Molecular Dynamic Simulations Reveal Different Features of IDO1 Structure

In the last decade, indoleamine 2,3‐dioxygenase 1 (IDO1) has attracted a great deal of attention being recognized as key regulator of immunosuppressive pathways in the tumor immuno‐editing process. Several classes of inhibitors have been developed as potential anticancer agents, but only few of them...

Descripción completa

Detalles Bibliográficos
Autores principales: Greco, Francesco Antonio, Bournique, Answald, Coletti, Alice, Custodi, Chiara, Dolciami, Daniela, Carotti, Andrea, Macchiarulo, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215573/
https://www.ncbi.nlm.nih.gov/pubmed/27546049
http://dx.doi.org/10.1002/minf.201501038