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Tolerogenic Plasmacytoid Dendritic Cells Control Paracoccidioides brasiliensis Infection by Inducting Regulatory T Cells in an IDO-Dependent Manner

Plasmacytoid dendritic cells (pDCs), considered critical for immunity against viruses, were recently associated with defense mechanisms against fungal infections. However, the immunomodulatory function of pDCs in pulmonary paracoccidiodomycosis (PCM), an endemic fungal infection of Latin America, ha...

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Detalles Bibliográficos
Autores principales: de Araújo, Eliseu Frank, Medeiros, Daniella Helena, Galdino, Nayane Alves de Lima, Condino-Neto, Antônio, Calich, Vera Lúcia Garcia, Loures, Flávio Vieira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215616/
https://www.ncbi.nlm.nih.gov/pubmed/27992577
http://dx.doi.org/10.1371/journal.ppat.1006115