Comparison of the Pharmacological Profiles of Selective PDE4B and PDE4D Inhibitors in the Central Nervous System

Inhibition of cyclic AMP (cAMP)-specific phosphodiesterase 4 (PDE4) has been proposed as a potential treatment for a series of neuropsychological conditions such as depression, anxiety and memory loss. However, the specific involvement of each of the PDE4 subtypes (PDE4A, 4B and 4C) in different cat...

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Detalles Bibliográficos
Autores principales: Zhang, Chong, Xu, Ying, Zhang, Han-Ting, Gurney, Mark E., O’Donnell, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215650/
https://www.ncbi.nlm.nih.gov/pubmed/28054669
http://dx.doi.org/10.1038/srep40115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215650/
https://www.ncbi.nlm.nih.gov/pubmed/28054669
http://dx.doi.org/10.1038/srep40115

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