Complement C3 on microglial clusters in multiple sclerosis occur in chronic but not acute disease: Implication for disease pathogenesis

Microglial clusters with C3d deposits are observed in the periplaque of multiple sclerosis (MS) brains and were proposed as early stage of lesion formation. As such they should appear in the brain of MS donors with acute disease but thus far this has not been shown. Using postmortem brain tissue fro...

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Detalles Bibliográficos
Autores principales: Michailidou, Iliana, Naessens, Daphne M. P., Hametner, Simon, Guldenaar, Willemijn, Kooi, Evert‐Jan, Geurts, Jeroen J. G., Baas, Frank, Lassmann, Hans, Ramaglia, Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215693/
https://www.ncbi.nlm.nih.gov/pubmed/27778395
http://dx.doi.org/10.1002/glia.23090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215693/
https://www.ncbi.nlm.nih.gov/pubmed/27778395
http://dx.doi.org/10.1002/glia.23090

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