Keratin-associated protein 5-5 controls cytoskeletal function and cancer cell vascular invasion

Cancer cell vascular invasion is a crucial step in the malignant progression towards metastasis. Here we used a genome-wide RNAi screen with E0771 mammary cancer cells to uncover drivers of endothelial monolayer invasion. We identified keratin-associated protein 5-5 (Krtap5-5) as a candidate. Krtap5...

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Detalles Bibliográficos
Autores principales: Berens, Eric B., Sharif, Ghada M., Schmidt, Marcel O., Yan, Gai, Shuptrine, Casey W., Weiner, Louis M., Glasgow, Eric, Riegel, Anna T., Wellstein, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215748/
https://www.ncbi.nlm.nih.gov/pubmed/27375028
http://dx.doi.org/10.1038/onc.2016.234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215748/
https://www.ncbi.nlm.nih.gov/pubmed/27375028
http://dx.doi.org/10.1038/onc.2016.234

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