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TRIM32-Cytoplasmic-Body Formation Is an ATP-Consuming Process Stimulated by HSP70 in Cells

The spontaneous and energy-releasing reaction of protein aggregation is typically prevented by cellular quality control machinery (QC). TRIM32 is a member of the TRIM (tripartite motif-containing) ubiquitin E3 ligases, and when overexpressed in cultured cells, readily forms spherical inclusions desi...

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Detalles Bibliográficos
Autores principales: Kawaguchi, Yuki, Taoka, Masato, Takekiyo, Takahiro, Uekita, Takamasa, Shoji, Ikuo, Hachiya, Naomi, Ichimura, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215751/
https://www.ncbi.nlm.nih.gov/pubmed/28052117
http://dx.doi.org/10.1371/journal.pone.0169436