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Phosphorylation regulates the sensitivity of voltage‐gated Kv7.2 channels towards phosphatidylinositol‐4,5‐bisphosphate

KEY POINTS: Phosphatidylinositol‐4,5‐bisphosphate (PIP(2)) is a key regulator of many membrane proteins, including voltage‐gated Kv7.2 channels. In this study, we identified the residues in five phosphorylation sites and their corresponding protein kinases, the former being clustered within one of f...

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Detalles Bibliográficos
Autores principales: Salzer, Isabella, Erdem, Fatma Asli, Chen, Wei‐Qiang, Heo, Seok, Koenig, Xaver, Schicker, Klaus W., Kubista, Helmut, Lubec, Gert, Boehm, Stefan, Yang, Jae‐Won
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215842/
https://www.ncbi.nlm.nih.gov/pubmed/27621207
http://dx.doi.org/10.1113/JP273274