Zinc Modulates Endotoxin-Induced Human Macrophage Inflammation through ZIP8 Induction and C/EBPβ Inhibition

Two vital functions of the innate immune system are to initiate inflammation and redistribute micronutrients in favor of the host. Zinc is an essential micronutrient used in host defense. The zinc importer ZIP8 is uniquely induced through stimulation of the NF-κB pathway by LPS in monocytes and func...

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Detalles Bibliográficos
Autores principales: Pyle, Charlie J., Akhter, Saife, Bao, ShengYing, Dodd, Claire E., Schlesinger, Larry S., Knoell, Daren L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215883/
https://www.ncbi.nlm.nih.gov/pubmed/28056086
http://dx.doi.org/10.1371/journal.pone.0169531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215883/
https://www.ncbi.nlm.nih.gov/pubmed/28056086
http://dx.doi.org/10.1371/journal.pone.0169531

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