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Soluble B and T Lymphocyte Attenuator Correlates to Disease Severity in Sepsis and High Levels Are Associated with an Increased Risk of Mortality

INTRODUCTION AND AIMS: B- and T-lymphocyte Attenuator (BTLA), Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and Programmed Death 1 (PD-1) are co-inhibitory receptors that regulate T cell activation. In the present study of ICU-treated patients we measured plasma concentrations of their solubl...

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Detalles Bibliográficos
Autores principales: Lange, Anna, Sundén-Cullberg, Jonas, Magnuson, Anders, Hultgren, Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5215942/
https://www.ncbi.nlm.nih.gov/pubmed/28056053
http://dx.doi.org/10.1371/journal.pone.0169176