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Opioid-Induced Bowel Dysfunction in Patients Undergoing Spine Surgery: Comparison of Oxycodone and Oxycodone-Naloxone Treatment

INTRODUCTION: Opioids are needed for postoperative pain in spine surgery patients, but opioid-induced constipation is a harmful adverse event. The aim of this clinical trial was to compare the use of a controlled-release oxycodone-naloxone combination product with oxycodone controlled-release tablet...

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Detalles Bibliográficos
Autores principales: Kokki, Merja, Kuronen, Moona, Naaranlahti, Toivo, Nyyssönen, Timo, Pikkarainen, Ira, Savolainen, Sakari, Kokki, Hannu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216064/
https://www.ncbi.nlm.nih.gov/pubmed/27921252
http://dx.doi.org/10.1007/s12325-016-0456-9