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Generation and differentiation of induced pluripotent stem cells reveal ankylosing spondylitis risk gene expression in bone progenitors

Axial spondyloarthritis (axSpA), which encompasses ankylosing spondylitis, is a complex genetic disease. Aberrant bone formation is a key feature of pathogenesis that can lead to ankylosis of the spine. Our objective is to determine, whether genes whose variants confer susceptibility to AS are expre...

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Detalles Bibliográficos
Autores principales: Layh-Schmitt, Gerlinde, Lu, Shajia, Navid, Fatemeh, Brooks, Stephen R., Lazowick, Emily, Davis, Kathryn M., Montagna, Cristina, Gadina, Massimo, Colbert, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216109/
https://www.ncbi.nlm.nih.gov/pubmed/27864696
http://dx.doi.org/10.1007/s10067-016-3469-5