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Generation and differentiation of induced pluripotent stem cells reveal ankylosing spondylitis risk gene expression in bone progenitors
Axial spondyloarthritis (axSpA), which encompasses ankylosing spondylitis, is a complex genetic disease. Aberrant bone formation is a key feature of pathogenesis that can lead to ankylosis of the spine. Our objective is to determine, whether genes whose variants confer susceptibility to AS are expre...
Autores principales: | Layh-Schmitt, Gerlinde, Lu, Shajia, Navid, Fatemeh, Brooks, Stephen R., Lazowick, Emily, Davis, Kathryn M., Montagna, Cristina, Gadina, Massimo, Colbert, Robert A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer London
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216109/ https://www.ncbi.nlm.nih.gov/pubmed/27864696 http://dx.doi.org/10.1007/s10067-016-3469-5 |
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