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Cell division orientation is coupled to cell–cell adhesion by the E-cadherin/LGN complex

Both cell–cell adhesion and oriented cell division play prominent roles in establishing tissue architecture, but it is unclear how they might be coordinated. Here, we demonstrate that the cell–cell adhesion protein E-cadherin functions as an instructive cue for cell division orientation. This is med...

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Detalles Bibliográficos
Autores principales: Gloerich, Martijn, Bianchini, Julie M., Siemers, Kathleen A., Cohen, Daniel J., Nelson, W. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216124/
https://www.ncbi.nlm.nih.gov/pubmed/28045117
http://dx.doi.org/10.1038/ncomms13996