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The mitotic kinesin-14 KlpA contains a context-dependent directionality switch

Kinesin-14s are commonly known as nonprocessive minus end-directed microtubule motors that function mainly for mitotic spindle assembly. Here we show using total internal reflection fluorescence microscopy that KlpA—a kinesin-14 from Aspergillus nidulans—is a context-dependent bidirectional motor. K...

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Detalles Bibliográficos
Autores principales: Popchock, Andrew R., Tseng, Kuo-Fu, Wang, Pan, Karplus, P. Andrew, Xiang, Xin, Qiu, Weihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216134/
https://www.ncbi.nlm.nih.gov/pubmed/28051135
http://dx.doi.org/10.1038/ncomms13999