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Iron alters valvular interstitial cell function and is associated with calcification in aortic stenosis

AIMS: Aortic valve stenosis (AS) is the most common valvulopathy and is characterized by inflammation, extracellular matrix (ECM) remodelling and calcification, causing a narrowing of the valve and the consequential obstruction of the cardiac outflow. Although intraleaflet haemorrhage is associated...

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Detalles Bibliográficos
Autores principales: Laguna-Fernandez, Andres, Carracedo, Miguel, Jeanson, Gregoire, Nagy, Edit, Eriksson, Per, Caligiuri, Giuseppina, Franco-Cereceda, Anders, Bäck, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216198/
https://www.ncbi.nlm.nih.gov/pubmed/27091952
http://dx.doi.org/10.1093/eurheartj/ehw122