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Iron alters valvular interstitial cell function and is associated with calcification in aortic stenosis
AIMS: Aortic valve stenosis (AS) is the most common valvulopathy and is characterized by inflammation, extracellular matrix (ECM) remodelling and calcification, causing a narrowing of the valve and the consequential obstruction of the cardiac outflow. Although intraleaflet haemorrhage is associated...
Autores principales: | Laguna-Fernandez, Andres, Carracedo, Miguel, Jeanson, Gregoire, Nagy, Edit, Eriksson, Per, Caligiuri, Giuseppina, Franco-Cereceda, Anders, Bäck, Magnus |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216198/ https://www.ncbi.nlm.nih.gov/pubmed/27091952 http://dx.doi.org/10.1093/eurheartj/ehw122 |
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