C-terminus of HSC70-Interacting Protein (CHIP) Inhibits Adipocyte Differentiation via Ubiquitin- and Proteasome-Mediated Degradation of PPARγ

PPARγ (Peroxisome proliferator-activated receptor γ) is a nuclear receptor involved in lipid homeostasis and related metabolic diseases. Acting as a transcription factor, PPARγ is a master regulator for adipocyte differentiation. Here, we reveal that CHIP (C-terminus of HSC70-interacting protein) su...

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Detalles Bibliográficos
Autores principales: Kim, Jung-Hoon, Shin, Soyeon, Seo, Jinho, Lee, Eun-Woo, Jeong, Manhyung, Lee, Min-sik, Han, Hyun-Ji, Song, Jaewhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216347/
https://www.ncbi.nlm.nih.gov/pubmed/28059128
http://dx.doi.org/10.1038/srep40023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216347/
https://www.ncbi.nlm.nih.gov/pubmed/28059128
http://dx.doi.org/10.1038/srep40023

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