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C-terminus of HSC70-Interacting Protein (CHIP) Inhibits Adipocyte Differentiation via Ubiquitin- and Proteasome-Mediated Degradation of PPARγ
PPARγ (Peroxisome proliferator-activated receptor γ) is a nuclear receptor involved in lipid homeostasis and related metabolic diseases. Acting as a transcription factor, PPARγ is a master regulator for adipocyte differentiation. Here, we reveal that CHIP (C-terminus of HSC70-interacting protein) su...
Autores principales: | Kim, Jung-Hoon, Shin, Soyeon, Seo, Jinho, Lee, Eun-Woo, Jeong, Manhyung, Lee, Min-sik, Han, Hyun-Ji, Song, Jaewhan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216347/ https://www.ncbi.nlm.nih.gov/pubmed/28059128 http://dx.doi.org/10.1038/srep40023 |
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