Tyrosine kinase c-Abl regulates the survival of plasma cells

Tyrosine kinase c-Abl plays an important role in early B cell development. Its deletion leads to reduced pro- and pre-B cell generation in mice. However, its function in B cell terminal differentiation remains unexplored. Here, we used c-Abl(f/f) Aicda(cre/+) mice, in which c-Abl is ablated only in...

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Detalles Bibliográficos
Autores principales: Li, Yan-Feng, Xu, Shengli, Huang, Yuhan, Ou, Xijun, Lam, Kong-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216354/
https://www.ncbi.nlm.nih.gov/pubmed/28057924
http://dx.doi.org/10.1038/srep40133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216354/
https://www.ncbi.nlm.nih.gov/pubmed/28057924
http://dx.doi.org/10.1038/srep40133

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