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Tyrosine kinase c-Abl regulates the survival of plasma cells
Tyrosine kinase c-Abl plays an important role in early B cell development. Its deletion leads to reduced pro- and pre-B cell generation in mice. However, its function in B cell terminal differentiation remains unexplored. Here, we used c-Abl(f/f) Aicda(cre/+) mice, in which c-Abl is ablated only in...
Autores principales: | Li, Yan-Feng, Xu, Shengli, Huang, Yuhan, Ou, Xijun, Lam, Kong-Peng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216354/ https://www.ncbi.nlm.nih.gov/pubmed/28057924 http://dx.doi.org/10.1038/srep40133 |
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