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Meprin β contributes to collagen deposition in lung fibrosis

Lung fibrosis is a severe disease characterized by epithelial cell injury, inflammation and collagen deposition. The metalloproteases meprinα and meprinβ have been shown to enhance collagen maturation and inflammatory cell infiltration via cleavage of cell-cell contact molecules; therefore we hypoth...

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Detalles Bibliográficos
Autores principales: Biasin, V., Wygrecka, M., Marsh, L. M., Becker-Pauly, C., Brcic, L., Ghanim, B., Klepetko, W., Olschewski, A., Kwapiszewska, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216360/
https://www.ncbi.nlm.nih.gov/pubmed/28059112
http://dx.doi.org/10.1038/srep39969