Membrane translocation of t-SNARE protein syntaxin-4 abrogates ground-state pluripotency in mouse embryonic stem cells

Embryonic stem (ES) and induced pluripotent stem (iPS) cells are attractive tools for regenerative medicine therapies. However, aberrant cell populations that display flattened morphology and lose ground-state pluripotency often appear spontaneously, unless glycogen synthase kinase 3β (GSK3β) and mi...

Descripción completa

Detalles Bibliográficos
Autores principales: Hagiwara-Chatani, Natsumi, Shirai, Kota, Kido, Takumi, Horigome, Tomoatsu, Yasue, Akihiro, Adachi, Naoki, Hirai, Yohei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216394/
https://www.ncbi.nlm.nih.gov/pubmed/28057922
http://dx.doi.org/10.1038/srep39868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216394/
https://www.ncbi.nlm.nih.gov/pubmed/28057922
http://dx.doi.org/10.1038/srep39868

Ejemplares similares