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Single cell time-lapse analysis reveals that podoplanin enhances cell survival and colony formation capacity of squamous cell carcinoma cells

Tumor initiating cells (TICs) are characterized by high clonal expansion capacity. We previously reported that podoplanin is a TIC-specific marker for the human squamous cell carcinoma cell line A431. The aim of this study is to explore the molecular mechanism underlying the high clonal expansion po...

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Detalles Bibliográficos
Autores principales: Miyashita, Tomoyuki, Higuchi, Youichi, Kojima, Motohiro, Ochiai, Atsushi, Ishii, Genichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216406/
https://www.ncbi.nlm.nih.gov/pubmed/28059107
http://dx.doi.org/10.1038/srep39971