N-n-butyl Haloperidol Iodide Protects against Hypoxia/Reoxygenation Injury in Cardiac Microvascular Endothelial Cells by Regulating the ROS/MAPK/Egr-1 Pathway

Endothelium dysfunction induced by reactive oxygen species (ROS) is an important initial event at the onset of myocardial ischemia/reperfusion in which the Egr-1 transcription factor often serves as a master switch for various damage pathways following reperfusion injury. We hypothesized that an int...

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Detalles Bibliográficos
Autores principales: Lu, Shishi, Zhang, Yanmei, Zhong, Shuping, Gao, Fenfei, Chen, Yicun, Li, Weiqiu, Zheng, Fuchun, Shi, Ganggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216659/
https://www.ncbi.nlm.nih.gov/pubmed/28111550
http://dx.doi.org/10.3389/fphar.2016.00520

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216659/
https://www.ncbi.nlm.nih.gov/pubmed/28111550
http://dx.doi.org/10.3389/fphar.2016.00520

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