Targeting cancer stem cells with p53 modulators

Cancer stem cells (CSC) typically over-express aldehyde dehydrogenase (ALDH). Thus, ALDH(bright) tumor cells represent targets for developing novel cancer prevention/treatment interventions. Loss of p53 function is a common genetic event during cancer development wherein small molecular weight compo...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Zhan, Liu, Ling, Gomez-Casal, Roberto, Wang, Xinhui, Hayashi, Ryo, Appella, Ettore, Kopelovich, Levy, DeLeo, Albert B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216707/
https://www.ncbi.nlm.nih.gov/pubmed/27074569
http://dx.doi.org/10.18632/oncotarget.8650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216707/
https://www.ncbi.nlm.nih.gov/pubmed/27074569
http://dx.doi.org/10.18632/oncotarget.8650

Ejemplares similares