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Targeting cancer stem cells with p53 modulators

Cancer stem cells (CSC) typically over-express aldehyde dehydrogenase (ALDH). Thus, ALDH(bright) tumor cells represent targets for developing novel cancer prevention/treatment interventions. Loss of p53 function is a common genetic event during cancer development wherein small molecular weight compo...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhan, Liu, Ling, Gomez-Casal, Roberto, Wang, Xinhui, Hayashi, Ryo, Appella, Ettore, Kopelovich, Levy, DeLeo, Albert B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216707/ https://www.ncbi.nlm.nih.gov/pubmed/27074569 http://dx.doi.org/10.18632/oncotarget.8650

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