Radiosensitization of HNSCC cells by EGFR inhibition depends on the induction of cell cycle arrests

The increase in cellular radiosensitivity by EGF receptor (EGFR) inhibition has been shown to be attributable to the induction of a G1-arrest in p53-proficient cells. Because EGFR targeting in combination with radiotherapy is used to treat head and neck squamous cell carcinomas (HNSCC) which are pre...

Descripción completa

Detalles Bibliográficos
Autores principales: Kriegs, Malte, Kasten-Pisula, Ulla, Riepen, Britta, Hoffer, Konstantin, Struve, Nina, Myllynen, Laura, Braig, Friederike, Binder, Mascha, Rieckmann, Thorsten, Grénman, Reidar, Petersen, Cordula, Dikomey, Ekkehard, Rothkamm, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216710/
https://www.ncbi.nlm.nih.gov/pubmed/27281611
http://dx.doi.org/10.18632/oncotarget.9161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216710/
https://www.ncbi.nlm.nih.gov/pubmed/27281611
http://dx.doi.org/10.18632/oncotarget.9161

Ejemplares similares