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GRK3 is a direct target of CREB activation and regulates neuroendocrine differentiation of prostate cancer cells

Neuroendocrine prostate cancer (NEPC) is an aggressive subtype of prostate cancer that commonly arises through neuroendocrine differentiation (NED) of prostate adenocarcinoma (PAC) after therapy, such as radiation therapy and androgen deprivation treatment (ADT). No effective therapeutic is availabl...

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Detalles Bibliográficos
Autores principales: Sang, Meixiang, Hulsurkar, Mohit, Zhang, Xiaochong, Song, Haiping, Zheng, Dayong, Zhang, Yan, Li, Min, Xu, Jianming, Zhang, Songlin, Ittmann, Michael, Li, Wenliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216714/
https://www.ncbi.nlm.nih.gov/pubmed/27191986
http://dx.doi.org/10.18632/oncotarget.9359