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MicroRNA-20a-5p promotes colorectal cancer invasion and metastasis by downregulating Smad4

BACKGROUND: Tumor metastasis is one of the leading causes of poor prognosis for colorectal cancer (CRC) patients. Loss of Smad4 contributes to aggression process in many human cancers. However, the underlying precise mechanism of aberrant Smad4 expression in CRC development is still little known. RE...

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Detalles Bibliográficos
Autores principales: Cheng, Dantong, Zhao, Senlin, Tang, Huamei, Zhang, Dongyuan, Sun, Hongcheng, Yu, Fudong, Jiang, Weiliang, Yue, Ben, Wang, Jingtao, Zhang, Meng, Yu, Yang, Liu, Xisheng, Sun, Xiaofeng, Zhou, Zongguang, Qin, Xuebin, Zhang, Xin, Yan, Dongwang, Wen, Yugang, Peng, Zhihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216716/
https://www.ncbi.nlm.nih.gov/pubmed/27286257
http://dx.doi.org/10.18632/oncotarget.9900