Role of FOXO1 in aldosterone-induced autophagy: A compensatory protective mechanism related to podocyte injury

This study was undertaken to elucidate whether and how autophagy was regulated in aldosterone (Aldo)-induced podocyte injury and to examine its role in this model both in vitro and in vivo. In cultured podocytes, Aldo increased autophagy flux as indicated by the enhanced expression of LC3-II/LC3-I a...

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Detalles Bibliográficos
Autores principales: Wang, Bin, Ding, Wei, Zhang, Minmin, Li, Hongmei, Guo, Honglei, Lin, Lilu, Chen, Jing, Gu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216726/
https://www.ncbi.nlm.nih.gov/pubmed/27244896
http://dx.doi.org/10.18632/oncotarget.9644

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216726/
https://www.ncbi.nlm.nih.gov/pubmed/27244896
http://dx.doi.org/10.18632/oncotarget.9644

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