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Gastrin-induced miR-222 promotes gastric tumor development by suppressing p27(kip1)

BACKGROUND AND AIMS: Elevated circulating concentrations of the hormone gastrin contribute to the development of gastric adenocarcinoma and types-1 and 2 gastric neuroendocrine tumors (NETs). MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate proteins which in turn inf...

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Detalles Bibliográficos
Autores principales: Lloyd, Katie A., Moore, Andrew R., Parsons, Bryony N., O'Hara, Adrian, Boyce, Malcolm, Dockray, Graham J., Varro, Andrea, Pritchard, D. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216734/
https://www.ncbi.nlm.nih.gov/pubmed/27323780
http://dx.doi.org/10.18632/oncotarget.9990