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Gastrin-induced miR-222 promotes gastric tumor development by suppressing p27(kip1)
BACKGROUND AND AIMS: Elevated circulating concentrations of the hormone gastrin contribute to the development of gastric adenocarcinoma and types-1 and 2 gastric neuroendocrine tumors (NETs). MicroRNAs (miRNAs) are small non-coding RNAs that post-transcriptionally regulate proteins which in turn inf...
Autores principales: | Lloyd, Katie A., Moore, Andrew R., Parsons, Bryony N., O'Hara, Adrian, Boyce, Malcolm, Dockray, Graham J., Varro, Andrea, Pritchard, D. Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216734/ https://www.ncbi.nlm.nih.gov/pubmed/27323780 http://dx.doi.org/10.18632/oncotarget.9990 |
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