Fibrotic microenvironment promotes the metastatic seeding of tumor cells via activating the fibronectin 1/secreted phosphoprotein 1-integrin signaling

The seeding of tumor cells is a critical step in the process of metastasis, but whether and how the microenvironment of target organs affects metastatic seeding remain largely unknown. Based on cell and mouse models, we found that the metastatic seeding and outgrowth of tumor cells were significantl...

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Detalles Bibliográficos
Autores principales: Zhang, Chong, Wu, Mengzhi, Zhang, Lizhen, Shang, Li-Ru, Fang, Jian-Hong, Zhuang, Shi-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216754/
https://www.ncbi.nlm.nih.gov/pubmed/27329720
http://dx.doi.org/10.18632/oncotarget.10157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216754/
https://www.ncbi.nlm.nih.gov/pubmed/27329720
http://dx.doi.org/10.18632/oncotarget.10157

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