The relevance of using 3D cell cultures, in addition to 2D monolayer cultures, when evaluating breast cancer drug sensitivity and resistance

Solid tumours naturally grow in 3D wherein the spatial arrangement of cells affects how they interact with each other. This suggests that 3D cell culture may mimic the natural in vivo setting better than traditional monolayer (2D) cell culture, where cells are grown attached to plastic. Here, using...

Descripción completa

Detalles Bibliográficos
Autores principales: Breslin, Susan, O'Driscoll, Lorraine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216757/
https://www.ncbi.nlm.nih.gov/pubmed/27304190
http://dx.doi.org/10.18632/oncotarget.9935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216757/
https://www.ncbi.nlm.nih.gov/pubmed/27304190
http://dx.doi.org/10.18632/oncotarget.9935

Ejemplares similares