Cargando…

NF-Y loss triggers p53 stabilization and apoptosis in HPV18-positive cells by affecting E6 transcription

The expression of the high risk HPV18 E6 and E7 oncogenic proteins induces the transformation of epithelial cells, through the disruption of p53 and Rb function. The binding of cellular transcription factors to cis-regulatory elements in the viral Upstream Regulatory Region (URR) stimulates E6/E7 tr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Benatti, Paolo, Basile, Valentina, Dolfini, Diletta, Belluti, Silvia, Tomei, Margherita, Imbriano, Carol
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216769/ https://www.ncbi.nlm.nih.gov/pubmed/27323853 http://dx.doi.org/10.18632/oncotarget.9974

Ejemplares similares

Specific inhibition of NF-Y subunits triggers different cell proliferation defects
por: Benatti, Paolo, et al.
Publicado: (2011)

Concurrent inhibition of enzymatic activity and NF-Y-mediated transcription of Topoisomerase-IIα by bis-DemethoxyCurcumin in cancer cells
por: Belluti, S, et al.
Publicado: (2013)

A balance between NF-Y and p53 governs the pro- and anti-apoptotic transcriptional response
por: Benatti, Paolo, et al.
Publicado: (2008)

The transcription factor NF-Y participates to stem cell fate decision and regeneration in adult skeletal muscle
por: Rigillo, Giovanna, et al.
Publicado: (2021)

Gain-of-function p53 mutants have widespread genomic locations partially overlapping with p63
por: Martynova, Elena, et al.
Publicado: (2012)

NF-Y activates genes of metabolic pathways altered in cancer cells
por: Benatti, Paolo, et al.
Publicado: (2015)

Alternative splicing of NF-YA promotes prostate cancer aggressiveness and represents a new molecular marker for clinical stratification of patients
por: Belluti, Silvia, et al.
Publicado: (2021)

bis-Dehydroxy-Curcumin Triggers Mitochondrial-Associated Cell Death in Human Colon Cancer Cells through ER-Stress Induced Autophagy
por: Basile, Valentina, et al.
Publicado: (2013)

Histone Marks-Dependent Effect on Alternative Splicing: New Perspectives for Targeted Splicing Modulation in Cancer?
por: Imbriano, Carol, et al.
Publicado: (2022)

Transcription Factors in Cancer: When Alternative Splicing Determines Opposite Cell Fates
por: Belluti, Silvia, et al.
Publicado: (2020)

Nuclear Estrogen Receptors in Prostate Cancer: From Genes to Function
por: Belluti, Silvia, et al.
Publicado: (2023)

Overexpression and alternative splicing of NF-YA in breast cancer
por: Dolfini, Diletta, et al.
Publicado: (2019)

NF-Y coassociates with FOS at promoters, enhancers, repetitive elements, and inactive chromatin regions, and is stereo-positioned with growth-controlling transcription factors
por: Fleming, Joseph D., et al.
Publicado: (2013)

NF-Y joins E2Fs, p53 and other stress transcription factors at the apoptosis table
por: Gatta, R, et al.
Publicado: (2011)

NF-YA Overexpression in Lung Cancer: LUAD
por: Bezzecchi, Eugenia, et al.
Publicado: (2020)

BAG3 down-modulation sensitizes HPV18(+) HeLa cells to PEITC-induced apoptosis and restores p53
por: Cotugno, Roberta, et al.
Publicado: (2014)

Potent Anti-Cancer Properties of Phthalimide-Based Curcumin Derivatives on Prostate Tumor Cells
por: Belluti, Silvia, et al.
Publicado: (2018)

NF-YA Overexpression in Lung Cancer: LUSC
por: Bezzecchi, Eugenia, et al.
Publicado: (2019)

NF-Y Overexpression in Liver Hepatocellular Carcinoma (HCC)
por: Bezzecchi, Eugenia, et al.
Publicado: (2020)

On the NF-Y regulome as in ENCODE (2019)
por: Ronzio, Mirko, et al.
Publicado: (2020)

The Switch from NF-YAl to NF-YAs Isoform Impairs Myotubes Formation
por: Libetti, Debora, et al.
Publicado: (2020)

NF-Y subunits overexpression in gastric adenocarcinomas (STAD)
por: Gallo, Alberto, et al.
Publicado: (2021)

Epitranscriptomics as a New Layer of Regulation of Gene Expression in Skeletal Muscle: Known Functions and Future Perspectives
por: Imbriano, Carol, et al.
Publicado: (2023)

NF-Y Recruits Ash2L to Impart H3K4 Trimethylation on CCAAT Promoters
por: Fossati, Andrea, et al.
Publicado: (2011)

NF-Y Subunits Overexpression in HNSCC
por: Bezzecchi, Eugenia, et al.
Publicado: (2021)

Corrigendum: Histone deacetylase functions and therapeutic implications for adult skeletal muscle metabolism
por: Molinari, Susanna, et al.
Publicado: (2023)

Histone deacetylase functions and therapeutic implications for adult skeletal muscle metabolism
por: Molinari, Susanna, et al.
Publicado: (2023)

A high definition look at the NF-Y regulome reveals genome-wide associations with selected transcription factors
por: Dolfini, Diletta, et al.
Publicado: (2016)

An NF-Y-Dependent Switch of Positive and Negative Histone Methyl Marks on CCAAT Promoters
por: Donati, Giacomo, et al.
Publicado: (2008)

The 1,10-Phenanthroline Ligand Enhances the Antiproliferative Activity of DNA-Intercalating Thiourea-Pd(II) and -Pt(II) Complexes Against Cisplatin-Sensitive and -Resistant Human Ovarian Cancer Cell Lines
por: Marverti, Gaetano, et al.
Publicado: (2019)

NF-YAl drives EMT in Claudin(low) tumours
por: Londero, Michela, et al.
Publicado: (2023)

Development of Stable Amino-Pyrimidine–Curcumin Analogs: Synthesis, Equilibria in Solution, and Potential Anti-Proliferative Activity
por: Mari, Matteo, et al.
Publicado: (2023)

Structural Basis of Inhibition of the Pioneer Transcription Factor NF-Y by Suramin
por: Nardone, Valentina, et al.
Publicado: (2020)

Curcumin improves the paclitaxel-induced apoptosis of HPV-positive human cervical cancer cells via the NF-κB-p53-caspase-3 pathway
por: DANG, YU-PING, et al.
Publicado: (2015)

Transcriptionally regulated and nontoxic delivery of the hyperactive Sleeping Beauty Transposase
por: Cocchiarella, Fabienne, et al.
Publicado: (2016)

Inhibitors of histone deacetylase 6 based on a novel 3-hydroxy-isoxazole zinc binding group
por: Linciano, Pasquale, et al.
Publicado: (2021)

Regulation of p53 Stability and Apoptosis by a ROR Agonist
por: Wang, Yongjun, et al.
Publicado: (2012)

E6/E7 and E6(*) From HPV16 and HPV18 Upregulate IL-6 Expression Independently of p53 in Keratinocytes
por: Artaza-Irigaray, Cristina, et al.
Publicado: (2019)

Dendrosomal nanocurcumin and p53 overexpression synergistically trigger apoptosis in glioblastoma cells
por: Keshavarz, Reihaneh, et al.
Publicado: (2016)

Does HPV 16/18 infection affect p53 expression in invasive ductal carcinoma? An experimental study
por: Hong, Liang, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_4k12fi8gsup38d9eavjo41u9qn