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miR146a-mediated targeting of FANCM during inflammation compromises genome integrity

Inflammation is a potent inducer of tumorigenesis. Increased DNA damage or loss of genome integrity is thought to be one of the mechanisms linking inflammation and cancer development. It has been suggested that NF-κB-induced microRNA-146 (miR146a) may be a mediator of the inflammatory response. Base...

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Detalles Bibliográficos
Autores principales: Sundaravinayagam, Devakumar, Kim, Hye Rim, Wu, TingTing, Kim, Hyun Hee, Lee, Hyun-Seo, Jun, Semo, Cha, Jeong-Heon, Kee, Younghoon, You, Ho Jin, Lee, Jung-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216775/
https://www.ncbi.nlm.nih.gov/pubmed/27351285
http://dx.doi.org/10.18632/oncotarget.10275