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miR146a-mediated targeting of FANCM during inflammation compromises genome integrity
Inflammation is a potent inducer of tumorigenesis. Increased DNA damage or loss of genome integrity is thought to be one of the mechanisms linking inflammation and cancer development. It has been suggested that NF-κB-induced microRNA-146 (miR146a) may be a mediator of the inflammatory response. Base...
Autores principales: | Sundaravinayagam, Devakumar, Kim, Hye Rim, Wu, TingTing, Kim, Hyun Hee, Lee, Hyun-Seo, Jun, Semo, Cha, Jeong-Heon, Kee, Younghoon, You, Ho Jin, Lee, Jung-Hee |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216775/ https://www.ncbi.nlm.nih.gov/pubmed/27351285 http://dx.doi.org/10.18632/oncotarget.10275 |
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