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Co-existence of IL7R high and SH2B3 low expression distinguishes a novel high-risk acute lymphoblastic leukemia with Ikaros dysfunction

Acute lymphoblastic leukemia (ALL) remains the leading cause of cancer-related death in children and young adults. Compared to ALL in children, adult ALL has a much lower cure rate. Therefore, it is important to understand the molecular mechanisms underlying high-risk ALL and to develop therapeutic...

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Detalles Bibliográficos
Autores principales: Ge, Zheng, Gu, Yan, Xiao, Lichan, Han, Qi, Li, Jianyong, Chen, Baoan, Yu, James, Kawasawa, Yuka Imamura, Payne, Kimberly J., Dovat, Sinisa, Song, Chunhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216778/
https://www.ncbi.nlm.nih.gov/pubmed/27322554
http://dx.doi.org/10.18632/oncotarget.10014