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Metformin mediates resensitivity to 5-fluorouracil in hepatocellular carcinoma via the suppression of YAP

Metformin plays an anti-proliferative role in tumor cells in many types of cancer. However, the correlation between metformin and sensitivity to chemotherapeutic agents in hepatocellular carcinoma (HCC) and the relevant mechanism are unclear. The present study showed that HCC patients with type 2 di...

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Detalles Bibliográficos
Autores principales: Tian, Yu, Tang, Bo, Wang, Chengye, Sun, Deguang, Zhang, Rixin, Luo, Nan, Han, Zhao, Liang, Rui, Gao, Zhenming, Wang, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216793/
https://www.ncbi.nlm.nih.gov/pubmed/27323827
http://dx.doi.org/10.18632/oncotarget.10079