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Metformin mediates resensitivity to 5-fluorouracil in hepatocellular carcinoma via the suppression of YAP
Metformin plays an anti-proliferative role in tumor cells in many types of cancer. However, the correlation between metformin and sensitivity to chemotherapeutic agents in hepatocellular carcinoma (HCC) and the relevant mechanism are unclear. The present study showed that HCC patients with type 2 di...
Autores principales: | Tian, Yu, Tang, Bo, Wang, Chengye, Sun, Deguang, Zhang, Rixin, Luo, Nan, Han, Zhao, Liang, Rui, Gao, Zhenming, Wang, Liming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216793/ https://www.ncbi.nlm.nih.gov/pubmed/27323827 http://dx.doi.org/10.18632/oncotarget.10079 |
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