Epac1 links prostaglandin E(2) to β-catenin-dependent transcription during epithelial-to-mesenchymal transition

In epithelial cells, β-catenin is localized at cell-cell junctions where it stabilizes adherens junctions. When these junctions are disrupted, β-catenin can translocate to the nucleus where it functions as a transcriptional cofactor. Recent research has indicated that PGE(2) enhances the nuclear fun...

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Detalles Bibliográficos
Autores principales: Jansen, Sepp R., Poppinga, Wilfred J., de Jager, Wim, Lezoualc'h, Frank, Cheng, Xiaodong, Wieland, Thomas, Yarwood, Stephen J., Gosens, Reinoud, Schmidt, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216803/
https://www.ncbi.nlm.nih.gov/pubmed/27344171
http://dx.doi.org/10.18632/oncotarget.10128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216803/
https://www.ncbi.nlm.nih.gov/pubmed/27344171
http://dx.doi.org/10.18632/oncotarget.10128

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