Critical function of the necroptosis adaptor RIPK3 in protecting from intestinal tumorigenesis

Necroptosis is a programmed form of non-apoptotic cell death that requires the kinase activity of the receptor interacting protein kinase 3 (RIPK3). Although in vitro data suggests that cancer cells lacking expression of RIPK3 are invasive, the physiological role of RIPK3 in a disease-relevant setti...

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Detalles Bibliográficos
Autores principales: Bozec, Dominique, Iuga, Alina C., Roda, Giulia, Dahan, Stephanie, Yeretssian, Garabet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216805/
https://www.ncbi.nlm.nih.gov/pubmed/27344176
http://dx.doi.org/10.18632/oncotarget.10135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216805/
https://www.ncbi.nlm.nih.gov/pubmed/27344176
http://dx.doi.org/10.18632/oncotarget.10135

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