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Critical function of the necroptosis adaptor RIPK3 in protecting from intestinal tumorigenesis
Necroptosis is a programmed form of non-apoptotic cell death that requires the kinase activity of the receptor interacting protein kinase 3 (RIPK3). Although in vitro data suggests that cancer cells lacking expression of RIPK3 are invasive, the physiological role of RIPK3 in a disease-relevant setti...
Autores principales: | Bozec, Dominique, Iuga, Alina C., Roda, Giulia, Dahan, Stephanie, Yeretssian, Garabet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216805/ https://www.ncbi.nlm.nih.gov/pubmed/27344176 http://dx.doi.org/10.18632/oncotarget.10135 |
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