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A mechanism for 1,4-Benzoquinone-induced genotoxicity

Benzene is a common environmental toxin and its metabolite, 1-4-Benzoquinone (BQ) causes hematopoietic cancers like myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). BQ has not been comprehensively assessed for its impact on genome maintenance, limiting our understanding of the true h...

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Detalles Bibliográficos
Autores principales: Son, Mi Young, Deng, Chu-Xia, Hoeijmarkers, Jan H., Rebel, Vivienne I., Hasty, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216808/
https://www.ncbi.nlm.nih.gov/pubmed/27340773
http://dx.doi.org/10.18632/oncotarget.10184