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Characterisation of the oxysterol metabolising enzyme pathway in mismatch repair proficient and deficient colorectal cancer

Oxysterols are oxidised derivatives of cholesterol, formed by the enzymatic activity of several cytochrome P450 enzymes and tumour-derived oxysterols have been implicated in tumour growth and survival. The aim of this study was to profile the expression of oxysterol metabolising enzymes in primary c...

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Detalles Bibliográficos
Autores principales: Swan, Rebecca, Alnabulsi, Abdo, Cash, Beatriz, Alnabulsi, Ayham, Murray, Graeme I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216813/
https://www.ncbi.nlm.nih.gov/pubmed/27341022
http://dx.doi.org/10.18632/oncotarget.10224