Delta-9-tetrahydrocannabinol protects against MPP(+) toxicity in SH-SY5Y cells by restoring proteins involved in mitochondrial biogenesis

Proliferator-activated receptor γ (PPARγ) activation can result in transcription of proteins involved in oxidative stress defence and mitochondrial biogenesis which could rescue mitochondrial dysfunction in Parkinson's disease (PD). The PPARγ agonist pioglitazone is protective in models of PD;...

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Detalles Bibliográficos
Autores principales: Zeissler, Marie-Louise, Eastwood, Jordan, McCorry, Kieran, Hanemann, C. Oliver, Zajicek, John P., Carroll, Camille B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216821/
https://www.ncbi.nlm.nih.gov/pubmed/27366949
http://dx.doi.org/10.18632/oncotarget.10314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216821/
https://www.ncbi.nlm.nih.gov/pubmed/27366949
http://dx.doi.org/10.18632/oncotarget.10314

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