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Strengths and weaknesses of EST-based prediction of tissue-specific alternative splicing
BACKGROUND: Alternative splicing contributes significantly to the complexity of the human transcriptome and proteome. Computational prediction of alternative splice isoforms are usually based on EST sequences that also allow to approximate the expression pattern of the related transcripts. However,...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC521684/ https://www.ncbi.nlm.nih.gov/pubmed/15453915 http://dx.doi.org/10.1186/1471-2164-5-72 |