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Strengths and weaknesses of EST-based prediction of tissue-specific alternative splicing

BACKGROUND: Alternative splicing contributes significantly to the complexity of the human transcriptome and proteome. Computational prediction of alternative splice isoforms are usually based on EST sequences that also allow to approximate the expression pattern of the related transcripts. However,...

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Detalles Bibliográficos
Autores principales: Gupta, Shobhit, Zink, Dorothea, Korn, Bernhard, Vingron, Martin, Haas, Stefan A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC521684/
https://www.ncbi.nlm.nih.gov/pubmed/15453915
http://dx.doi.org/10.1186/1471-2164-5-72