Loss of T-cell quiescence by targeting Slfn2 prevents the development and progression of T-ALL

T-cell acute lymphoblastic leukemia (T-ALL) is an aggressive malignancy of thymocytes. Despite significant improvement in the treatment of T-ALL, approximately 20% of children and most adults undergo relapse. Previous findings demonstrated that loss of T-cell quiescence due to a mutation in the Slfn...

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Detalles Bibliográficos
Autores principales: Goldshtein, Aviya, Zerbib, Shani Mistriel, Omar, Ibrahim, Cohen-Daniel, Leonor, Popkin, Daniel, Berger, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216906/
https://www.ncbi.nlm.nih.gov/pubmed/27206675
http://dx.doi.org/10.18632/oncotarget.9390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216906/
https://www.ncbi.nlm.nih.gov/pubmed/27206675
http://dx.doi.org/10.18632/oncotarget.9390

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