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AIM2 inhibits autophagy and IFN-β production during M. bovis infection

Mycobacteria can trigger the AIM2 inflammasome, autophagy activation and type-I interferon release, which are both activated by cytosolic DNA. We have recently demonstrated that activation of the AIM2 inflammasome during M. bovis infection is the result of mycobacterial translocation into the cytoso...

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Detalles Bibliográficos
Autores principales: Liu, Chunfa, Yue, Ruichao, Yang, Yang, Cui, Yongyong, Yang, Lifeng, Zhao, Deming, Zhou, Xiangmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216917/
https://www.ncbi.nlm.nih.gov/pubmed/27409673
http://dx.doi.org/10.18632/oncotarget.10503