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A Phosphatidic Acid (PA) conveyor system of continuous intracellular transport from cell membrane to nucleus maintains EGF receptor homeostasis

The intracellular concentration of the mitogen phosphatidic acid (PA) must be maintained at low levels until the need arises for cell proliferation. How temporal and spatial trafficking of PA affects its target proteins in the different cellular compartments is not fully understood. We report that i...

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Detalles Bibliográficos
Autores principales: Henkels, Karen M., Miller, Taylor E., Ganesan, Ramya, Wilkins, Brandon A., Fite, Kristen, Gomez-Cambronero, Julian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5216919/
https://www.ncbi.nlm.nih.gov/pubmed/27256981
http://dx.doi.org/10.18632/oncotarget.9685